Keir Dullea

Dr. David Bowman

Gary Lockwood

Dr. Frank Poole

William Sylvester

Dr. Heywood Floyd

Douglas Rain

HAL 9000 (voice)

Daniel Richter

Moonwatcher

Leonard Rossiter

Dr. Andrei Smyslov

Margaret Tyzack

Elena

Robert Beatty

Dr. Ralph Halvorsen

Sean Sullivan

Dr. Roy Michaels

Frank Miller

Mission Controller

Ed Bishop

Aries-1B Lunar Shuttle Captain

Edwina Carroll

Aries-1B Stewardess

Heather Downham

Stewardess

Penny Brahms

Stewardess

Maggie London

Stewardess

Chela Matthison

Stewardess

Alan Gifford

Poole's Father

Ann Gillis

Poole's Mother

Vivian Kubrick

Floyd's daughter (uncredited)

Kenneth Kendall

BBC-12 Announcer

Kevin Scott

Miller

Bill Weston

Astronaut

Glenn Beck

Astronaut

David Charkham

Ape

Péter Delmár

Ape

Terry Duggan

Ape Attacked by Leopard

David Hines

Ape

Bob Wilyman

Ape

Richard Woods

Ape Killed by Moon-Watcher

Sheraton Blount

(uncredited)

Ann Bormann

(uncredited)

Julie Croft

(uncredited)

Penny Francis

(uncredited)

Marcella Markham

(uncredited)

Irena Marr

Russian Scientist (uncredited)

Burnell Tucker

TMA-1 Site Photographer (uncredited)

John Swindells

TMA-1 Site Technician #1 (uncredited)

John Clifford

TMA-1 Site Technician #2 (uncredited)

Stanley Kubrick

(voice) (uncredited)

Anthony Jackson

Ape

Harry Fielder

Moonwalker (uncredited)