Joseph Gordon-Levitt

Adam Lerner

Seth Rogen

Kyle Hirons

Anna Kendrick

Katherine McKay

Bryce Dallas Howard

Rachael

Philip Baker Hall

Alan

Serge Houde

Richard Lerner

Andrew Airlie

Dr. Ross

Matt Frewer

Mitch

Peter Kelamis

Phil

Jessica Parker Kennedy

Jackie

Anjelica Huston

Diane Lerner

Sugar Lyn Beard

Susan

Donna Yamamoto

Dr. Walderson

Yee Jee Tso

Dr. Lee

Sarah Smyth

Jenny

Daniel Bacon

Dr. Phillips

P. Lynn Johnson

Bernie

Laura Bertram

Claire

Matty Finochio

Ted

Marie Avgeropoulos

Allison

Luisa d'Oliveira

Agabelle Loogenburgen

Veena Sood

Nurse Stewart

Andrea Brooks

Attractive Woman #2

Beatrice King

Pretty Girl

Chilton Crane

Mother on the Bus

Lauren Miller Rogen

Bodie

Brent Sheppard

Minister

Stephanie Belding

Friendly Nurse

William 'Big Sleeps' Stewart

George

Amitai Marmorstein

Young Person on the Bus

Stephen Colbert

Self (archive footage) (uncredited)

D. C. Douglas

Live Volcano Reporter (voice) (uncredited)

Cameron K. Smith

Chemo Patient (uncredited)