Matt Damon

Paul Safranek

Christoph Waltz

Dusan Mirkovic

Hong Chau

Ngoc Lan Tran

Kristen Wiig

Audrey Safranek

Rolf Lassgård

Dr. Jorgen Asbjørnsen

Ingjerd Egeberg

Anne-Helene Asbjørnsen

Udo Kier

Konrad

Søren Pilmark

Dr. Andreas Jacobsen

Jason Sudeikis

Dave Johnson

Maribeth Monroe

Carol Johnson

Jayne Houdyshell

Paul's Mother

Phil Reeves

Audrey's Dad Larry

James Van Der Beek

Anesthesiologist

Tim Driscoll

Good Friend Tim

Patrick Gallagher

Drunk Guy at Bar

Michael Heathcote

Carrying Box Carrier

Martha Girvin

Curious Reunion Friend

Brendan Beiser

Reunion Friend

Alison Brooks

Reunion Friend

Neil Patrick Harris

Jeff Lonowski

Laura Dern

Laura Lonowski

Niecy Nash-Betts

Leisureland Salesperson

Margo Martindale

Woman on Shuttle

Kerri Kenney

Single Mom Kristen

Donna Lynne Champlin

Leisureland Administrator

Don Lake

Leisureland Guide Matt

Mary Kay Place

Land's End Customer (voice)

Kerry-Lee Finkle

Downsizing Nurse

Jon De Leon

Keepsake Box Mover

Jeff Clarke

Divorce Lawyer

Juan Carlos Velis

Call Center Co-Worker

Paul Mabon

Olive Garden Roger

Veena Sood

Leislureland Housewife

Brigette Lundy-Paine

Dusan's Girlfriend

Kristina Cocoli

Dusan's Party Girl

Jeffrey R. Smith

Guy at Dusan's Party

Pepe Serna

Señor Cárdenas

Rose Bianco

Gladys

Joaquim de Almeida

Conference Director Dr. Pereira

Cameron Geddes

Little Ronni

Warren Belle

Tunde

Ksenia Daniela Kharlamova

Colony Member

Hélène Cardona

Newscaster (uncredited)