Lindsay Lohan

Cady Heron

Rachel McAdams

Regina George

Lizzy Caplan

Janis Ian

Lacey Chabert

Gretchen Wieners

Amanda Seyfried

Karen Smith

Daniel Franzese

Damian Leigh

Jonathan Bennett

Aaron Samuels

Rajiv Surendra

Kevin Gnapoor

Tim Meadows

Mr. Duvall

Tina Fey

Ms. Norbury

Ana Gasteyer

Cady's Mom

Neil Flynn

Cady's Dad

Amy Poehler

Mrs. George

Ky Pham

Trang Pak

Dwayne Hill

Coach Carr

Diego Klattenhoff

Shane Oman

Alexandra Stapley

Taylor Wedell

Laura de Carteret

Mrs. Wedell

Molly Shanahan

Kristen Hadley

Elana Shilling

Spelling Girl

Graham Kartna

Homeschooled Boy

Ely Henry

Homeschooled Boy

David Aherne

Homeschooled Boy

Ayo Agbonkpolo

African Warrior

Jonathan Malen

Kristen Hadley's Boyfriend

Jeff Moser

Farting Guy

Danielle Nguyen

Sun Jin Dinh

Miranda Edwards

Michigan Girl

Les Porter

Chemistry Teacher

Eve Crawford

English Teacher

Jack Newman

History Teacher

Michelyn Emelle

Music Teacher

Bathsheba Garnett

German Teacher

Daniel DeSanto

Jason

Alisha Morrison

Lea Edwards

Chris Anton

Huge Guy

Jan Caruana

Emma Gerber

Wai Choy

Tim Pak

Julia Chantrey

Amber D'Alessio

Jacky Chamberlain

Giselle Sgro

Olympia Lukis

Jessica Lopez

Stefanie Drummond

Bethany Byrd

Kristen Bone

Short Girl

Jessie Wright

Five-Year-Old Cady

Tyson Fennell

Nfume

Andreja Punkris

Animal Dancer

Noelle Boggio

Animal Dancer

Jordan Dawe

Animal Dancer

Nicole Crimi

Kylie George

Erin Norah Thompson

Dawn Schweitzer

Dan Willmott

Mr. George

Michelle Hoffman

Kissing Girl

Valerie Casault

Kissing Girl

Sharron Matthews

Joan

Bruce Hunter

Mathlete Moderator

Jo Chim

Salesperson

Randi Lee Butcher

Skater Girl

Erin Jarvis

Skater Girl

Kaylen Christensen

Jock Girl

Jill Morrison

Crying Girl

David Sazant

Marymount Captain

Clare Preuss

Caroline Krafft

Megan Millington

Junior Plastic

Tara Shelley

Junior Plastic

Shannon Todd

Junior Plastic

David Reale

Glenn Coco (uncredited)

Krysta Carter

Wannabe (uncredited)