Hilary Swank

Claire Morgan

Robert De Niro

Stan Harris

Michelle Pfeiffer

Ingrid Withers

Josh Duhamel

Sam

Sarah Jessica Parker

Kim Doyle

Zac Efron

Paul

Lea Michele

Elise

Ashton Kutcher

Randy

Halle Berry

Nurse Aimee

Jon Bon Jovi

Daniel Jensen

Katherine Heigl

Laura Carrington

Seth Meyers

Griffin Byrne

Jessica Biel

Tess Byrne

Til Schweiger

James Schwab

Carla Gugino

Spiritual Dr. Morriset

Cary Elwes

Stan's Doctor

Sofía Vergara

Ava

Hector Elizondo

Kominsky

Abigail Breslin

Hailey Doyle

Ludacris

Brendan

Sarah Paulson

Grace Schwab

Alyssa Milano

Nurse Mindy

Jake T. Austin

Seth

Katherine McNamara

Lily Bowman

Nat Wolff

Walter

Yeardley Smith

Maude

Ryan Seacrest

Self

Michael Bloomberg

Self

Jim Belushi

Building Super

Mara Davi

Mika

Russell Peters

Chef Sunil

Common

Soldier

Jackie Seiden

Bride Trish

Joey McIntyre

Groom Rory

Beth Kennedy

Piper's Mom

Larry Miller

Harley (segment "Ahern Party")

Christine Lakin

Waitress Alyssa

Shea Curry

Wendy

Sandra Taylor

Patty

Matthew Broderick

Mr. Buellerton (uncredited)

John Lithgow

Jonathan Cox (uncredited)

Juliette Angelo

Sadie

Barbara Marshall

Head Nurse Helen

Penny Marshall

Penny Marshall

Cherry Jones

Mrs Rose Ahern

Michael Mandell

Murray (segment "Resolution Tour")