Edward Norton

Will Graham

Anthony Hopkins

Hannibal Lecter

Ralph Fiennes

Francis Dolarhyde / Red Dragon

Emily Watson

Reba McClane

Harvey Keitel

Jack Crawford

Philip Seymour Hoffman

Freddy Lounds

Anthony Heald

Dr. Frederick Chilton

Mary-Louise Parker

Molly Graham

Tyler Patrick Jones

Josh Graham

Ken Leung

Lloyd Bowman

Frankie Faison

Barney Matthews

Lalo Schifrin

Conductor

John Rubinstein

Dinner Guest

David Doty

Dinner Guest

Brenda Strong

Dinner Guest

Robert Curtis Brown

Dinner Guest

Mary Anne McGarry

Dinner Guest

Marc Abraham

Dinner Guest

Veronica De Laurentiis

Dinner Guest

Michael Cavanaugh

Forensic Dentist

Madison Mason

Police Commissioner

Bill Duke

Police Chief

Azura Skye

Bookseller

Stanley Anderson

Jimmy Price

Jeanine Jackson

Dr. Hassler

Ellen Burstyn

Grandma Dolarhyde (voice) (uncredited)

Mary Beth Hurt

Museum Curator (uncredited)

James Pickens Jr.

Male Zoo Doctor (uncredited)

Frank Whaley

Ralph Mandy (uncredited)

Tanya Newbould

Chromalux Secretary

Katie Rich

Woman Detective

Tom Verica

Charles Leeds

Marguerite MacIntyre

Valerie Leeds

Elizabeth Dennehy

Beverly

William Lucking

Byron Metcalf

Joseph Simmons

Janitor

Mark Moses

Father in Video

Lisa Thornhill

Mrs. Sherman

Ronald Fischer

Driver (uncredited)

Alex D. Linz

Young Dolarhyde (voice)