Hailee Steinfeld

Gwen Stacy (voice)

Brian Tyree Henry

Jeff Morales (voice)

Luna Lauren Velez

Rio Morales (voice)

Oscar Isaac

Miguel O'Hara (voice)

Jake Johnson

Peter B. Parker (voice)

Jason Schwartzman

Spot (voice)

Daniel Kaluuya

Hobie Brown (voice)

Nicolas Cage

Spider-Man Noir (voice)

Amandla Stenberg

Margo Kess (voice)

Karan Soni

Pavitr Prabhakar (voice)

Mahershala Ali

Uncle Aaron (voice)

Greta Lee

LYLA (voice)

Andy Samberg

Ben Reilly (voice)

Shea Whigham

George Stacy (voice)