Frank Welker

Scooby-Doo / Fred Jones (voice)

Grey DeLisle

Daphne Blake / Wonder Woman (voice)

Matthew Lillard

Shaggy Rogers (voice)

Kate Micucci

Velma Dinkley (voice)

P.J. Byrne

J.B. (voice)

Victoria Grace

Mercy (voice)

Charles Halford

Lex Luthor (voice)

Nolan North

Computer / Joker / Superman (voice)

Tara Strong

Helen / Lois Lane / Harley Quinn (voice)

Fred Tatasciore

Solomon Grundy / Perry White (voice)

James Arnold Taylor

Jimmy Olsen / Rex Ruthor (voice)

Niccole Thurman

Mayor Flemming (voice)

Sam Vincent

Krypto (voice)

Brian Drummond

Streaky (voice)

Scott McNeil

Ace (voice)