Paul Rudd

Jeff Reigert

Adam Brody

Stephen Montgomery

Jon Hamm

Skydiving Guide Chris Knarl

Winona Ryder

Kelly La Fonda

Ken Marino

Dr. Glenn Richie

Mather Zickel

Louis La Fonda

Ali Marsh

'Entertainment Beat' Host George Reardon

Ron Silver

Fielding Barnes

Jason Antoon

Salazar 'Fred' McBairn

Andrea Rosen

Polly 'Carol' Samuels

Chris Wylde

Kevin Lipworth

Siri Baruc

Party Girl Natalie Freyberg

Reed Birney

Jim Stansel

Erica Oyama

Breem Benson

Famke Janssen

Gretchen Reigert

Gretchen Mol

Gloria Jennings

A.D. Miles

Oliver Jennings

Jason Sudeikis

Tony Contiella

Justin Theroux

Jesus H. Christ

Tommy Nelson

Noah Jennings

Liev Schreiber

Ray Johnson

Zak Orth

Prosecutor / Tour Guide Barge Michaelson

Beth Dover

Sheila Contiella

Novella Nelson

Judge Sophia R. Jackson

Scott Sowers

Jury Foreman Barry Noodle

Michael Mulheren

Carvin 'Big Buster' Waggle

Jessica Alba

Liz Anne Blazer

Kerri Kenney

Bernice Jaffe

Cedric Sanders

Greg Jaffe

Arlen Escarpeta

Todd Jaffe

Oliver Platt

Marc Jacobson

David Wain

Abe Grossman / Cartoon Voices

Thomas Lennon

Scotty Pale

Zandy Hartig

Sally Johnson / Callie Mardino / Cartoon Voices

Joe Lo Truglio

Paul Mardino

Charlie McDermott

Jake Johnson

Janeane Garofalo

Nuclear Powerplant Shift Supervisor Beth Soden

Rob Corddry

Duane Rosenblum

Michael Ian Black

Prison Guard Jamberg Saivon

Rashida Jones

Hostess Rebecca Fornier

Michael Showalter

Police Lt. Flarn Bleern

John Tormey

Junkie Jerry Park

Philip Levy

Junkie Tommy 'Thomas' McKee

H. Jon Benjamin

Lying Rhino (voice)

Bobby Cannavale

Marty McBride

Robert Ben Garant

Self