John Wayne

Capt. Nathan Cutting Brittles

Joanne Dru

Olivia Dandridge

John Agar

Lt. Flint Cohill

Ben Johnson

Sgt. Tyree

Harry Carey, Jr.

2nd Lt. Ross Pennell

Victor McLaglen

First Sergeant Quincannon

Mildred Natwick

Abby Allshard ("Old Iron Pants")

George O’Brien

Maj. Mac Allshard

Arthur Shields

Dr. O'Laughlin

Michael Dugan

Sgt. Hochbauer

Chief John Big Tree

Chief Pony That Walks

Fred Graham

Sgt. Hench

Tom Tyler

Cpl. Mike Quayne

Noble Johnson

Chief Red Shirt

Paul Fix

Gunrunner (uncredited)

Francis Ford

Connelly - Fort Stark Suttlers Barman (uncredited)

Cliff Lyons

Trooper Cliff (uncredited)

Frank McGrath

Bugler / Indian (uncredited)

Irving Pichel

Narrator (voice) (uncredited)

Jack Tornek

Officer (uncredited)

Dan White

Trooper (uncredited)

Harry Woods

Karl Rynders (uncredited)

Rudy Bowman

Pvt. John Smith - aka Rome Clay (uncredited)

Ray Hyke

Trooper McCarthy (uncredited)

Fred Libby

Cpl. Krumrein (uncredited)

Jack Pennick

Sergeant Major (uncredited)

Mickey Simpson

Cpl. Wagner (uncredited)