Gary Cooper

Henry Louis 'Lou' Gehrig

Teresa Wright

Eleanor Twitchell

Babe Ruth

Babe Ruth

Walter Brennan

Sam Blake

Dan Duryea

Hank Hanneman

Elsa Janssen

Christina 'Mom' Gehrig

Ludwig Stössel

Henry 'Pop' Gehrig

Virginia Gilmore

Myra Tinsley

Pierre Watkin

Mr. Twitchell

Harry Harvey

Joe McCarthy

Addison Richards

Coach

Hardie Albright

Van Tuyl

Edward Fielding

Clinic Doctor

Edgar Barrier

Hospital Doctor

Gene Collins

Billy (Age 8)

David Holt

Billy (Age 17)

Lynton Brent

Photographer in Hospital (uncredited)

Roy Brent

Yankee Ballplayer (uncredited)

Don Brodie

Girl Show Barker (uncredited)

Charles Cane

Plumber (uncredited)

Jack Carr

Plumber (uncredited)

Eddy Chandler

Motorcycle Cop #2 (uncredited)

Lane Chandler

Mark - Player in Locker Room (uncredited)

Spencer Charters

Mr. Larsen (uncredited)

Dane Clark

Fraternity Boy (uncredited)

Heinie Conklin

Wallpaper Hanger (uncredited)

John Daheim

Reporter in Hospital (uncredited)

Lester Dorr

Disappointed Fan #1 (uncredited)

Frank Faylen

Yankee Third Base Coach (uncredited)

Walter Fenner

Dentist (uncredited)

Pat Flaherty

Yankee Ballplayer (uncredited)

Vaughan Glaser

Doctor in Gehrig Home (uncredited)

Mary Gordon

Maid (uncredited)

Herschel Graham

Spectator (uncredited)

Eddie Hall

Reporter in Hospital Room (uncredited)

Harry Hayden

Department Store Manager (uncredited)

Vinton Hayworth

Fraternity Boy (uncredited)

Oscar 'Dutch' Hendrian

Furniture Mover (uncredited)

Earle Hodgins

Bottle Game Operator (uncredited)

John Ince

Man in Box Seat (uncredited)

Mitchell Ingraham

Barber (uncredited)

John Kellogg

Fraternity Boy (uncredited)

Colin Kenny

Yankee Player on Train (uncredited)

Rex Lease

Spectator (uncredited)

Theodore Lorch

Neighbor Leaning Through Window (uncredited)

Wilbur Mack

Man Outside Yankee Stadium (uncredited)

Ralph McCullough

Reporter in Hospital (uncredited)

Matt McHugh

Strength Machine Operator (uncredited)

Wilmuth Merkyl

Spectator (uncredited)

Tom Neal

Fraternity Boy (uncredited)

George Offerman, Jr.

Freshman (uncredited)

Emory Parnell

Chicago Policeman O'Doul (uncredited)

Edward Peil Sr.

Policeman (uncredited)

Tom Quinn

Reporter in Hospital (uncredited)

Cyril Ring

Photographer (uncredited)

Henry Roquemore

Disappointed Fan #2 (uncredited)

Anita Sharp-Bolster

Sasha's Mother (uncredited)

Jack Shea

Hammond (uncredited)

John Sheehan

First Paper Hanger (uncredited)

Brick Sullivan

Policeman (uncredited)

Dorothy Vaughan

Eleanor's Landlady (uncredited)

Malcolm Waite

Big Strength Machine Contestant (uncredited)

James Westerfield

Spectator (uncredited)

Guy Wilkerson

Sportsman at Ballgame (uncredited)

Max Willenz

Mr. Colletti (uncredited)

Charles Williams

Little Strength Machine Contestant (uncredited)

Dick Gordon

Radio Listener (uncredited)