Steve Carell

Gru (voice)

Miranda Cosgrove

Margo (voice)

Dana Gaier

Edith (voice)

Elsie Fisher

Agnes (voice)

Jason Segel

Vector (voice)

Russell Brand

Dr. Nefario (voice)

Julie Andrews

Gru's Mother (voice)

Will Arnett

Mr. Perkins (voice)

Kristen Wiig

Miss Hattie (voice)

Pierre Coffin

Tim / Bob / Mark / Phil / Stuart (voice)

Chris Renaud

Dave (voice)

Jemaine Clement

Jerry (voice)

Jack McBrayer

Carnival Barker / Tourist Dad (voice)

Danny McBride

Fred McDade (voice)

Mindy Kaling

Tourist Mom (voice)

Rob Huebel

Anchorman (voice)

Ken Daurio

Egyptian Guard (voice)

Ken Jeong

Talk Show Host (voice)

Charles Bright

Additional Voices (voice)

Katie Leigh

Additional Voices (voice)

Ranjani Brow

Additional Voices (voice)

Scott Menville

Additional Voices (voice)

Holly Dorff

Additional Voices (voice)

Edie Mirman

Additional Voices (voice)

Jackie Gonneau

Additional Voices (voice)

Al Rodrigo

Additional Voices (voice)

Wendy Hoffmann

Additional Voices (voice)

Jakob Roston

Additional Voices (voice)

James Kyson

Additional Voices (voice)

John Hans Tester

Additional Voices (voice)

Tony Lee

Additional Voices (voice)

Debi Mae West

Additional Voices (voice)