David Byrne

Narrator / Lip-Syncher

John Goodman

Louis Fyne

Annie McEnroe

Kay Culver

Jo Harvey Allen

The Lying Woman

Spalding Gray

Earl Culver

Alix Elias

The Cute Woman

Roebuck 'Pops' Staples

Mr. Tucker

Tito Larriva

Ramon

John Ingle

The Preacher

Matthew Posey

The Computer Guy

Swoosie Kurtz

The Lazy Woman

Jerry Harrison

Lip-Syncher

Tina Weymouth

Lip-Syncher

Chris Frantz

Lip-Syncher

Scott Valentine

Air Band

Gregory Gunter

Laughing Headline Reader #2

Ric Spiegel

Passerby in Mall

Ed Geldart

Grandfather in Mall

Jason Liebrecht

"Hey Now" Kid

John Pritchett

Sound Man

Louis Black

The Happy Wanderers Strictly Accordion Marching Band (uncredited)

Chris Douridas

Teenage Boy Ventriloquist (uncredited)

Leesa Rowland

Blonde in Nightclub (uncredited)