Leonardo DiCaprio

Howard Hughes

Cate Blanchett

Katharine Hepburn

Kate Beckinsale

Ava Gardner

John C. Reilly

Noah Dietrich

Alec Baldwin

Juan Trippe

Alan Alda

Senator Ralph Owen Brewster

Ian Holm

Professor Fitz

Danny Huston

Jack Frye

Gwen Stefani

Jean Harlow

Jude Law

Errol Flynn

Adam Scott

Johnny Meyer

Matt Ross

Glenn Odekirk

Kelli Garner

Faith Domergue

Frances Conroy

Mrs. Hepburn

Brent Spiner

Robert Gross

Stanley DeSantis

Louis B. Mayer

Edward Herrmann

Joseph Breen

Willem Dafoe

Roland Sweet

Kenneth Welsh

Dr. Hepburn

J.C. MacKenzie

Ludlow

Jacob Davich

Howard Hughes (9 yrs old)

Amy Sloan

Howard Hughes' Mother

Sam Hennings

HELL'S ANGELS Stunt Coordinator

Joe Chrest

HELL'S ANGELS Director of Photography

Rufus Wainwright

Cocoanut Grove Vocalist #1

Harry Strandjofski

Crony of Louis B. Mayer

Josie Maran

Cigarette Girl

Justin Shilton

HELL'S ANGELS Pilot

Arthur Holden

Radio Announcer

Joseph P. Reidy

Aide to Howard

Stéphane Demers

Maitre d'

Yves Jacques

Waiter

Loudon Wainwright III

Cocoanut Grove Vocalist #2

Jason Cavalier

Cocoanut Grove Patron

Chris Ufland

Engineer

Alan Toy

Man on Crutches

Sebastian Tillinger

Timer

Francesca Scorsese

Little Girl

James Bradford

Uncle Willy

Joe Cobden

Another Guest #1

Linda E. Smith

Another Guest #2

Alan Fawcett

Chairman MPA

David Purdham

Emcee

Kevin O'Rourke

Spencer Tracy

Lisa Bronwyn Moore

Noah's Wife

Emma Campbell

Jack Frye's Wife, Helen

Vincent Laresca

Jorge

Matt Holland

Hughes' Staff Person

Dennis St John

Custodian

Keith Campbell

Marine

Al Vandecruys

Doctor

Nellie Sciutto

Secretary

Terry Haig

Another Senator

John Koensgen

Pan Am Executive #2

Heather Petrone

Vivien Leigh (uncredited)

Elizabeth DeCicco

Starlet (uncredited)

Isabelle Champeau

Editor (uncredited)

Al Coronel

Bi-Plane Mechanic (uncredited)

Anne V. Coates

Howard Hughes' Film Editor (uncredited)