Leonard Nimoy

Self (archive footage)

William Shatner

Self

George Takei

Self

J.J. Abrams

Self

Simon Pegg

Self

Chris Pine

Self

Nichelle Nichols

Self

Zachary Quinto

Self

Zoe Saldaña

Self

Neil deGrasse Tyson

Self

Jim Parsons

Self

Jason Alexander

Self

Mayim Bialik

Self

Walter Koenig

Self

Nicholas Meyer

Self

Bill Prady

Self

Catherine Hicks

Self

Barry Newman

Self

Jeffrey Katzenberg

Self

Karl Urban

Self

James Duff

Self

Brooke Adams

Elizabeth Driscoll (archive footage)

James Arness

Matt Dillon (archive footage)

Majel Barrett

Number One (archive footage)

Avery Brooks

Benjamin Sisko (archive footage)

Kaley Cuoco

Penny (archive footage)

Ted Danson

Jack (archive footage)

James Doohan

Scotty (archive footage)

Terry Farrell

Jadzia Dax (archive footage)

Donald Sutherland

Matthew Bennell (archive footage)

William Windom

Commodore Decker (archive footage)

Tom Selleck

Peter (archive footage)

Liam Neeson

Leo Cutter (archive footage)

Christopher Lloyd

Commander Kruge (archive footage)

Jill Ireland

Leila Kalomi (archive footage)

Jeffrey Hunter

Captain Christopher Pike (archive footage)