Stephen Lang

George Herman 'Babe' Ruth

Brian Doyle-Murray

Marshall Hunt

Donald Moffat

Jacob Ruppert

Yvonne Suhor

Helen Woodford Ruth

Bruce Weitz

Miller Huggins

Lisa Zane

Claire Hodgson Ruth

William Lucking

Brother Matthias

Neal McDonough

Lou Gehrig

Pete Rose

Ty Cobb

Matthew Glave

Jumpin' Joe Dugan

Adam Goldberg

Vendor

John Anderson

Judge Landis

Gary A. Jones

Baseball Fan (uncredited)