Owen Wilson

Marmaduke (voice)

Emma Stone

Mazie (voice)

George Lopez

Carlos (voice)

Caroline Sunshine

Barbara Winslow

Finley Jacobsen

Brian Winslow

Steve Coogan

Raisin (voice)

Christopher Mintz-Plasse

Giuseppe (voice)

Fergie

Jezebel (voice)

Kiefer Sutherland

Bosco (voice)

Lee Pace

Phil Winslow

Judy Greer

Debbie Winslow

Damon Wayans Jr.

Thunder (voice)

Marlon Wayans

Lightning (voice)

Sam Elliott

Chupadogra (voice)

William H. Macy

Don Twombly

David Walliams

Anton Harrison

Glenn McCuen

Bodie

Raugi Yu

Drama Trainer

Chris Colfer

Drama Dog #2 (voice)

Josh Gad

Bandana Dog (voice)

Ash Lee

Male Executive

Heather Doerksen

Female Executive

Nicole Muñoz

3rd OC Girl

Frank Topol

Buff Owner

Izaak Smith

Basketball Captain

Keith Dallas

Emergency Road Worker

P.J. Prinsloo

Lead Fireman

Colin Decker

Fireman

Charles Jarman

Fireman

Garvin Cross

Fireman

Anjelah Johnson-Reyes

Afghan #2 (voice)

Devon Werkheiser

Drama Dog #1 / Shroom Dog #2 / Golden Dog / Cocker Spaniel (voice)

Hudson Thames

Delinquent Dog (voice)

Bernardo de Paula

Purse Dog #2 (voice)

Eddie 'Piolin' Sotelo

Purse Dog #3 (voice)

Jack McGee

Dalmatian (voice)

Liza Lapira

Party Dog #1 (voice)

King Kedar

Surfing Award Dog / Beach Dog #4 (voice)

Todd Glass

Doberman / Shasta (voice)

Ryan Devlin

Beach Dog #2 (voice)

Jeffrey Garcia

Beach Dog #3 (voice)