George Clooney

Michael Clayton

Tom Wilkinson

Arthur Edens

Tilda Swinton

Karen Crowder

Michael O'Keefe

Barry Grissom

Sydney Pollack

Marty Bach

Alberto Vazquez

Player #1

Brian Koppelman

Player #2

Tom McCarthy

Waiter (voice)

Denis O'Hare

Mr. Greer

Julie White

Mrs. Greer

Jennifer Van Dyck

Ivy

Frank Wood

Gerald

Bill Raymond

Gabe Zabel

Jonathan Walker

Del (voice)

Sharon Washington

Pam

Cynthia Mace

Wendy (voice)

Michael Countryman

Evan (voice)

Ken Howard

Don Jeffries

Amy Hargreaves

Interviewer

Rachel Black

Maude

John Douglas Thompson

Jail Guard

Merritt Wever

Anna

Christopher Mann

Lieutenant Elston

Katherine Waterston

Third Year

Remy Auberjonois

Fifth Year

Robert Prescott

Mr. Verne

Terry Serpico

Mr. Iker

Heidi Armbruster

Anna's Sister

Pamela Gray

Cindy Bach

Kevin Hagan

Raymond Clayton

Julia Gibson

Stephanie Clayton

Sean Cullen

Gene Clayton

David Lansbury

Timmy Clayton

David Zayas

Detective Dalberto

Douglas McGrath

Jeff Gaffney

Gregory Dann

Cop

Cathy Diane Tomlin

Cop #2

Sam Gilroy

Copy Kid

Maggie Siff

Attorney #1

Jordan Lage

Partner

Neal Huff

First Associate

Kevin Cannon

Auction Worker (uncredited)

Clem Cheung

Landlord (uncredited)

Tony Gilroy

Taxi Driver (voice) (uncredited)

Josh Mowery

Lawyer (uncredited)

Kimmy Suzuki

Copy Shop Clerk (uncredited)