Jason Segel

Gary

Amy Adams

Mary

Chris Cooper

Tex Richman

Rashida Jones

CDE Executive

Steve Whitmire

Kermit / Beaker / Statler / Rizzo / Link / Newsman (voice)

Peter Linz

Walter (voice)

Eric Jacobson

Miss Piggy / Fozzie / Animal / Sam Eagle / Marvin Suggs (voice)

Dave Goelz

Gonzo / Honeydew / Zoot / Beauregard / Waldorf (voice)

Bill Barretta

Swedish Chef / Rowlf / Teeth / Pepe / Bobo / Muppet Gary (voice)

David Rudman

Scooter / Janice / Miss Poogy / Wayne (voice)

Matt Vogel

Pepper / Camilla / Sweetums / Robot / Deadly / Harry (voice)

Alan Arkin

Tour Guide

Bill Cobbs

Grandfather

Zach Galifianakis

Hobo Joe

Ken Jeong

Punch Teacher Host

Jim Parsons

Human Walter

Eddie Pepitone

Postman

Kristen Schaal

Moderator

Sarah Silverman

Greeter

Eddie 'Piolin' Sotelo

TV Executive

Raymond Ma

Elderly Asian Man

Shu Lan Tuan

Elderly Asian Woman

Donald Glover

Junior CDE Executive

Dahlia Waingort

TV Executive

Jonathan Palmer

Reporter One

Michael Albala

TV Executive

Julia Marie Franzese

Punch Teacher Kid

Justin Marco

Gary Age 13

Justin Tinucci

Laughing Kid

Aria Noelle Curzon

Waitress

Emily Blunt

Miss Piggy's Receptionist

James Carville

James Carville

Leslie Feist

Smalltown Resident

Whoopi Goldberg

Whoopi Goldberg

Selena Gomez

Selena Gomez

Dave Grohl

Animool

Neil Patrick Harris

Neil Patrick Harris

Judd Hirsch

Judd Hirsch

John Krasinski

John Krasinski

Rico Rodriguez

Rico Rodriguez

Mickey Rooney

Smalltown Resident

Tyler Bunch

Fozzie Moopet / Thog / Additional Muppet Performer (voice)

Bruce Lanoil

Additional Muppet Performer (voice)

Michelan Sisti

Additional Muppet Performer (voice)

Paul McGinnis

Additional Muppet Performer (voice)

Tim Blaney

Additional Muppet Performer (voice)

Kevin Carlson

Additional Muppet Performer (voice)

Leslie Carrara-Rudolph

Additional Muppet Performer (voice)

Alice Dinnean

Afghan Hound / Wanda / Additional Muppet Performer (voice)

Julia Gunn

Additional Muppet Performer (voice)

BJ Guyer

Additional Muppet Performer (voice)

Tanya Haden

Additional Muppet Performer (voice)

James Murray

Additional Muppet Performer (voice)

Karen Prell

Additional Muppet Performer (voice)

Mike Quinn

Additional Muppet Performer (voice)

Andy Stone

Additional Muppet Performer (voice)

Jack Black

Jack Black (uncredited)

Mike Carlucci

Scout Troop Leader (uncredited)

Reese Hartwig

Punch Teacher Contestant (uncredited)

Jerry Nelson

Telethon Announcer (voice) (uncredited)