Joaquin Phoenix

Beau Wassermann

Patti LuPone

Mona Wassermann

Amy Ryan

Grace

Nathan Lane

Roger

Kylie Rogers

Toni

Denis Ménochet

Jeeves

Parker Posey

Elaine Bray

Zoe Lister-Jones

Young Mona

Armen Nahapetian

Teen Beau

Julia Antonelli

Teen Elaine

Stephen McKinley Henderson

Therapist

Richard Kind

Dr. Cohen

Hayley Squires

Penelope

Julian Richings

Strange Man

Bill Hader

UPS Guy

Catherine Bérubé

Hero Beau's Wife

Stephanie Herrera

Martha

Bradley Fisher

Birthday Boy Stab Man

Michael Esper

Officer Johnson

Manuel Tadros

Cheapo Depot Cashier

Marc-André Brisebois

Comatose Junkie

Tyrone Benskin

Rattled Businessman

Archie Madekwe

Laughing Man

Patrick Kwok-Choon

Orphan Hero

Michael Gandolfini

Beau’s Son

Théodore Pellerin

Beau’s Son

Mike Taylor

Beau’s Son

Kwasi Songui

Orphan Ladybug Man

Tristan D. Lalla

Costume Designer Orphan

Emmanuel Schwartz

Orphan Chorus Member

Cat Lemieux

Orphan Chorus Member

Lily Bird

Samanda

Arthur Holden

Duncan / God on Cloud / Hero Beau’s Wife

Alex Bisping

Orphan Production Designer

Joe Cobden

News Correspondent (Brian Galloway)

Harry Strandjofski

Superintendent / Catering Manager

Anana Rydvald

Teen Elaine's Mother

David Mamet

Rabbi

Karim Babin

Caterer

Gord Robertson

Monster Puppeteer

Pamela Iveta

Monster Puppeteer

Ari Aster

A Neighbor of Beau's (uncredited)