Ronald Colman

Dr. Martin Arrowsmith

Helen Hayes

Leora Tozer Arrowsmith

Alec B. Francis

Twyford

Claude King

Dr. Tubbs

Myrna Loy

Joyce Lanyon

Lumsden Hare

Sir Robert Fairland

Ward Bond

Cop (uncredited)

Beulah Bondi

Mrs. Tozer (uncredited)

Florence Britton

Miss Twyford (uncredited)

Nora Cecil

Nurse (uncredited)

Sidney De Gray

Dr. Hesselink (uncredited)

Cyril Delevanti

Committee Member (uncredited)

Gibson Gowland

Committee Member (uncredited)

Theresa Harris

Native Mother (uncredited)

Raymond Hatton

Drunk (uncredited)

George Humbert

Italian Uncle (uncredited)

DeWitt Jennings

B.W. Tozer (uncredited)

Mike Lally

Reporter (uncredited)

Eric Mayne

Dignitary at Luncheon (uncredited)

Kendall McComas

Little Johnny (uncredited)

Edmund Mortimer

Ship's Passenger (uncredited)

John Qualen

Henry Novak (uncredited)

Bobby Watson

Little Neighbor (uncredited)

Eric Wilton

Ship's Officer (uncredited)