Emily Blunt

Liza Drake

Chris Evans

Pete Brenner

Catherine O'Hara

Jackie

Andy García

Dr. Neel

Jay Duplass

Larkin

Brian d'Arcy James

Dr. Lydell

Amit Shah

Eric Paley

Chloe Coleman

Phoebe

Valerie LeBlanc

Laurene

Aubrey Dollar

Andy

Britt Rentschler

Camille

Michael Kosta

Guy Schatz

Nicholas Christopher McNeil

Randy

Chapel Oaks

Daughter

Selena Anduze

Kate

A.K. Benninghofen

Dr. Bowen

Chinet Scott

Nicole

Avis-Marie Barnes

Principal

Lydia Castro

Banker

Mandi Christine Kerr

Clinic RN

Andrea Laing

Ellen

Greyson Chadwick

Maria

Hillary Harley

Tina

Pat Dortch

Nervous Pain Clinic Doctor

Omer Mughal

Agent Simonetti

Cara Mantella

Admissions Officer

Dustin Lewis

Mr. Jorgenson

Alex Van

Patient Outside Lydell's Clinic

Quinn Bozza

Undercover D.E.A.

Donna DuPlantier

Jane Yagoda

Michael Lowry

Neel's Lawyer

David Kronawitter

Dr. Hartigan

Jackie Goldston

Judge

Leydi Morales

Loan Agent

Erin Ownbey

Young Jackie

Alan Wells

Gambling Anonymous Doctor

Sharon Conley

Judge Susan Holman

Desmond Phillips

Bartender

Nick Arapoglou

Bartender

Tris Marie

Lydell Nurse (uncredited)

Shelley Jane

Nervous Doctor's Crush (uncredited)