Dan Aykroyd

Louis Winthorpe III

Eddie Murphy

Billy Ray Valentine

Ralph Bellamy

Randolph Duke

Don Ameche

Mortimer Duke

Denholm Elliott

Coleman

Kristin Holby

Penelope Witherspoon

Paul Gleason

Clarence Beeks

Jamie Lee Curtis

Ophelia

Alfred Drake

President of Exchange

Bo Diddley

Pawnbroker

Frank Oz

Corrupt Cop

Jim Belushi

Harvey

Al Franken

Baggage Handler #1

Tom Davis

Baggage Handler #2

Sunnie Merrill

Duke & Duke Employee

Mary St. John

Duke & Duke Employee

Florence Anglin

Duke Domestic

Bobra Suiter

Duke Domestic

Walt Gorney

Duke Domestic

P. Jay Sidney

Heritage Club Doorman

Avon Long

Ezra

Tom Mardirosian

Officer Pantuzzi

Robert Curtis Brown

Todd

Nicholas Guest

Harry

John Bedford Lloyd

Andrew

Robert Earl Jones

Attendant

Peter Hock

Cop #2

Clint Smith

Doo Rag Lenny

Ron Taylor

Big Black Guy

Giancarlo Esposito

Cellmate #2

Steve Hofvendahl

Cellmate #3

James Eckhouse

Guard

Gwyllum Evans

President of Heritage Club

Eddie Jones

Cop #3

John McCurry

Cop #4

Michelle Mais

Hooker #1

Bill Cobbs

Bartender

Jacques Sandulescu

Creepy Man

Kelly Curtis

Muffy

Susan Fallender

Bunny

Lucianne Buchanan

President's Mistress

Jimmy Raitt

Ophelia's Client

Philip Bosco

Doctor

Bill Boggs

Newscaster

Don McLeod

Gorilla

Stephen Stucker

Stationmaster

Richard Hunt

Wilson

Paul Austin

Trader #1

John Randolph Jones

Trader #2

Jack Davidson

Trader #3

Bernie McInerney

Trader #4

Ralph Clanton

Official #1

Bryan Clark

Official #2

Gary Klar

Longshoreman

Afemo Omilami

Longshoreman

Donna Palmer

Gladys

Barry Dennen

Demitri

Benjean

Stray Dog (uncredited)

John Black

Man Sitting on Couch at Party (uncredited)

John Landis

Man with Briefcase (uncredited)

Charles Pendelton

Cop (uncredited)

Jan Saint

Man in Police Station (uncredited)

Arleen Sorkin

Woman at Party (uncredited)

Ronald Sylvers

Rolls Royce Driver (uncredited)

Marlene Willoughby

Woman Passed Out on Couch (uncredited)