Hrithik Roshan

Krishna Mehra / Krrish / Rohit Mehra

Priyanka Chopra Jonas

Priya Mehra

Vivek Oberoi

Kaal

Kangana Ranaut

Kaya

Arif Zakaria

Dr. Varun Shetty

Asif Basra

Dr. Alok Sen

Rajpal Yadav

Kripal Sharma

Rakhee Tandon

Sharma's Wife

Amitabh Bachchan

Narrator

Sachin Khedekar

Minister (Special Appearance)

Naseeruddin Shah

Dr. Siddhant Arya (Special Appearance)

Mohnish Behl

Kaal's Adoptive Father (Special Appearance)

Raju Kher

Dr. Alok Sen

Daniel Kaleb

Rhino Man