Seth Rogen

Frank / Sergeant Pepper (voice)

Kristen Wiig

Brenda (voice)

Jonah Hill

Carl (voice)

Bill Hader

Firewater / Tequila / El Guaco (voice)

Michael Cera

Barry (voice)

James Franco

Druggie (voice)

Danny McBride

Honey Mustard (voice)

Craig Robinson

Grits (voice)

Paul Rudd

Darren (voice)

Nick Kroll

Douche (voice)

David Krumholtz

Kareem Abdul Lavash (voice)

Edward Norton

Sammy Bagel Jr. (voice)

Salma Hayek Pinault

Teresa Taco (voice)

Anders Holm

Troy (voice)

Conrad Vernon

Toilet Paper / Sauerkraut / Catcall Sausage / Grape #1 / Beer Can / Pop Bottle (voice)

Lauren Miller Rogen

Camille Toh / Tampon (voice)

Greg Tiernan

Potato / Noodle Soup (voice)

Ian Hanlin

Beet (voice)

Maryke Hendrikse

Popped Cherry Mixer / Plum #1 / Loretta Bun / Frozen Fruitz (voice)